陈培林
陈培林

姓名:陈培林
职称/头衔:硕士
所属科室:生殖科
从业年限:
技术专长:微流控芯片单细胞分析、微流控芯片微量生物分子分析及相关技术在辅助生殖胚胎无创性评估选择的应用

个人简介

  分析化学硕士,助理研究员。深圳中山泌尿外科医院生殖临床研究中心、锦欣医疗科技创新中心科研人员。主要研究方向包括:胚胎分泌蛋白评估胚胎发育潜能的研究、微量蛋白定量检测方法研究、微流控在辅助生殖中的应用研究。

  业务领域:

  主要从事利用微流控等技术评估胚胎质量,优化胚胎培养体系的研究。

  学术成果:

  主持或参加科研项目(课题)及人才计划项目情况(按时间倒序排序):

  1、 中华医学会生殖医学青年医师研究与发展项目,18010120741,一种无创行胚胎植入潜能评估方案-基于囊胚培养液诱导子宫内膜分泌蛋白群的定量分析,20190630-20210630,在研,参与。

  2、 国家自然科学基金委青年科学基金项目、21807072,人类胚胎内源性硫化氢的无创实时检测及其调控胚胎发育的作用机制研究,20190101-20211231,在研,参与。

  代表性研究成果和学术奖励

  一、期刊论文

  1. 第一作者或通讯作者论文

  (1) Chen PL(#), Sun Q, Xiong F, Zhong HX, Yao ZH, Zeng Y(*). A method for the detection of hCG beta in spent embryo culture medium based on multicolor fluorescence detection from microfluidic droplets. Biomicrofluidics. 2020;14(2):024107.

  (2) 陈培林, 孙青, 熊风, 李观贵, 钟惠娴, 万才云, 姚志鸿, 曾勇.不同来源冷冻复苏精子ICSI后对囊胚培养结局的影响[J].生殖医学杂志,2019,(09):993-997.

  2.既非第一作者又非通讯作者论文

  (1) Zhong Huixian(#), Sun Qing(#), Chen Peilin, Xiong Feng, Li Guangui, Wan Caiyun, Yao Zhihong, Zeng Yong(*). Detection of IL-6, IL-10, and TNF-alpha level in human single-blastocyst conditioned medium using ultrasensitive Single Molecule Array platform and its relationship with embryo quality and implantation: a pilot study. J Assist Reprod Genet. 2020;37(7):1695-702.

  (2) Lu Li(#), Qingling Li(#), Peilin Chen, Zhongyi Li, Zhenzhen Chen, and Bo Tang(*). Consecutive Gated Injection-Based Microchip Electrophoresis for Simultaneous Quantitation of Superoxide Anion and Nitric Oxide in Single PC-12 Cells. Anal. Chem., 2016, 88, 930-936.

  (3) Qingling Li(#), Peilin Chen, Yuanyuan Fan, Xu Wang, Kehua Xu, Lu Li* and Bo Tang(*). Multi-Color Fluorescence Detection-Based Microfluidic Device for Single-Cell Metabolomics: Simultaneous Quantitation of Multiple Small Molecules in Primary Liver Cells. Anal. Chem., 2016, 88, 8610-8616.

  (4) Xiong F(#), Li GG, Sun Q, Chen PL, Wang Z, Wan CY, Yao ZH, Zhong H, Zeng Y(*). Obstetric and perinatal outcomes of pregnancies according to initial maternal serum HCG concentrations after vitrified-warmed single blastocyst transfer. Reprod Biomed Online. 2019;38(3):455-64.

  (5) Xiong F(#), Li GG, Sun Q, Wang SS, Wan CY, Chen PL, Yao ZH, Zhong HX, Zeng Y(*). Clinical outcomes after transfer of blastocysts derived from frozen-thawed cleavage embryos: a retrospective propensity-matched cohort study. Arch Gynecol Obstet. 2019;300(3):751-61.

  (6) Xiong F(#), Sun Q, Li GG, Chen PL, Yao ZH, Wan CY, Zhong HX, Zeng Y(*). Initial serum HCG levels are higher in pregnant women with a male fetus after fresh or frozen single blastocyst transfer: A retrospective cohort study. Taiwan J Obstet Gynecol. 2019;58(6):833-9.

  (7) Xiong F(#), Sun Q, Li GG, Yao ZH, Chen PL, Wan CY, Zhong HX, Zeng Y(*). Association between the number of top-quality blastocysts and live births after single blastocyst transfer in the first fresh or vitrified-warmed IVF/ICSI cycle. Reprod Biomed Online. 2020;40(4):530-7.

  (8) Xiong F(#), Wang SS, Sun Q, Ye L, Yao ZH, Chen PL, Wan CY, Zhong HX, Zeng Y(*). A visualized clinical model predicting good quality blastocyst development in the first IVF/ICSI cycle. Reprod Biomed Online. 2020;41(5):807-17.

  (9) Xiong F(#), Yao ZH, Chen PL, Sun Q, Zhong HX, Wan C, Zeng Y(*). Comparative secretome profile analysis of cultured immortalized human endometrial stromal cells supplemented with implanted versus nonimplanted blastocyst-conditioned medium: A preliminary analysis. J Obstet Gynaecol Res. 2020;46(9):1809-18.

  二、授权专利

  (1) 唐波,李清岭,李璐,陈培林,一种用于单细胞电泳芯片的双激光诱导荧光多色检测器,2019.07.23,国家发明专利,ZL 2016 1 0069047.2。